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Some patients are not able to tolerate sulfate because sulfate resembles oxygen and just as CFS patients are intolerant of oxygen, some patients are intolerant of sulfate

In addition, close monitoring and sedation scoring systems used to assess the level of sedation and adjust propofol infusion rates accordingly are recommended to minimize the prolonged use of propofol

The compounding industry argued, not unreasonably, that the restrictions had driven patients toward unregulated gray-market sources: overseas chemical suppliers operating under "research use only" labels with no quality controls, no dosage verification, and no pharmaceutical oversight